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Science: Scientific Scholarships

Every year, the ACB Scientific Committee is charged by the ACB Council to give financial support to young scientists in the profession undertaking relevant research. There is a small sum of money budgeted for this purpose. Applications normally open in May and close at the end of August. Scholarships are awarded at the September meeting of the Scientific Committee.

The number of applications we receive has increased year on year and, pleasingly, quality has also been on the rise although this then gives us the nice problem of selecting which studies to support.

2016 Round 

The 2016 round of ACB Scientific Scholarships is now closed.

2015 Round 

Application for the 2015 round of ACB Scientific Scholarships is now closed.
Below is a summary of successful applications:
  • Amy Dunne Development and validation of a high sensitivity oestradiol assay by tandem mass spectrometry.
  • David Taylor Serum steroid panel to improve the lateralisation of primary aldosteronism during adrenal venous sampling.
  • Elizabeth Ralph Improving outcomes in immune compromised patients: developing new diagnostic and monitoring tests for investigation of long-term immunological memory.
  • Emma Dewar Development of a LC-MS/MS Method for the Analysis of Ethanol Biomarkers in Post-Mortem Dried Blood Spots.
  • Harriet Claire Allison Antimicrobial pharmacokinetics in critically ill patients in an intensive care unit, including those receiving sustained low efficiency dialysis (SLED).
  • Joanne Morris A laboratory evaluation of a new test for measuring free light chains in blood samples.
  • Julianne Brown Gut microbiome in paediatric transplant patients.
  • Lewis Green The Development & Validation of an Automated Serum Procalcitonin immunoassay for use as a Diagnostic Marker for Bacterial sepsis and a Guide for Antimicrobial Stewardship.
  • Neil Robert Syme Development of a liquid chromatography tandem mass spectrometry method for measurement of human calcitonin in plasma.
  • Rachel Dale Substance Misuse in Pregnancy – Determining the Scale of the Problem.

Reports

The following project update reports have been received from past successful scholarship applicants:

PDF Danja Schulenburg-Brand - A pilot study to identify genetic factors that may be associated with increased risk of acute neurovisceral attacks in patients with Acute Intermittent Porphyria.

 

PDF Gemma Clark - The effect of genetic variability within the hepatitis B surface antigen on quantification: an evaluation of diagnostic and clinical impact.

 

PDF > Jane Armer - The performance of biochemical markers of alcohol use including carbohydrate deficient transferrin, ethyl glucuronide and ethyl sulphate to detect alcohol ingestion in clients in a community alcohol treatment programme.

 

To demonstrate the breadth and scope of studies for which we receive applications, below is a summary of the successful applications for 2009-2014.

2014


  • Victoria Miari Investigation of multi-site Neisseria gonorrhoeae infection and relationship of antimicrobial susceptibility profiles with NG-MAST.
  • Rebecca McCann Analytical assessment of a serum Calprotectin assay and its clinical utility as a screening tool for Inflammatory Bowel Disease.
  • Craig McKibbin Development of a tryptic peptide LC-MS/MS assay to quantitate IGF binding proteins and characterise changes in protein concentrations with nutritional status in the acute setting
  • Carol-Anne McInally The molecular epidemiology and clinical disease severity of infections with Human rhinoviruses in hospitalised children.
  • Andrew Chadburn Development and validation of Buhlmann faecal calprotectin ELISA kit for the measurement of serum calprotectin.
  • Christopher Parker What is the biological variation of novel markers of acute kidney injury (interleukin-18 and tissue inhibitor of metalloproteinases-2) in patients with chronic kidney disease?
  • Vaclav Stemberk Preliminary assessment of the KIM-1 lateral flow immunoassay performance as a potential POC tool for early AKI detection and disease progression monitoring.
  • Christopher Duff Development and evaluation of an App for patients with diabetes to optimise their long term monitoring.
  • Greg Toulson Evaluation of selected CSF proteins as prognostic markers of dementia in patients with Parkinson’s disease
  • Isla Wooton Quantification of Thyroglobulin in Serum Tandem Mass Spectrometry: A means to overcome Interference due to Anti-Thyroglobulin Autoantibodies?

 2013

  • Karolina Stepien, Manchester. The development of a method for the quantitation of progesterone in saliva by ultra high performance liquid chromatography tandem mass spectrometry
  • Amy Frank, Coventry. Plasma Allopregnanolone as a potential biomarker of postnatal depression in genetically vulnerable women
  • Danja Schulenburg-Brand, Cardiff. A pilot study to identify genetic factors that may be associated with increased risk of acute neurovisceral attacks in patients with Acute Intermittent Porphyria.
  • Emma Evans, Nottingham. Will a combination of renal biomarkers predict Acute Kidney Injury in critically ill patients?
  • Gary Woodward, Oxford. Evaluation of urine calprotectin as a marker of acute rejection of bladder-drained pancreas allografts
  • Jane Armer, Preston. The performance of biochemical markers of alcohol use including carbohydrate deficient transferrin, ethyl glucuronide and ethyl sulphate to detect alcohol ingestion in clients in a community alcohol treatment programme
  • Sarah Dowden, Birmingham. Development and evaluation of an LCMS/MS method for the analysis of Busulfan in plasma.
  • Gemma Clark, Nottingham. The effect of genetic variability within the hepatitis B surface antigen on quantification: an evaluation of diagnostic and clinical impact.

2012

  • Caroline Evans, Oxford Use of a functional memory B-cell ELISpot assay for the investigation of antibody responses in patients with Common Variable Immunodeficiency
  • Alexander Lawson, Birmingham Development of a method for the determination of hepcidin in serum using UPLC-MS/MS. Comparison to ESI-TOF measurements in patients with CKD, haemochromatosis and rheumatoid arthritis
  • Elaine Cloutman-Green, London Development of Adenovirus detection and typing systems to investigate the contribution of environmental contamination, cleaning and human behaviour in cross transmission
  • Dunstan Vincent, London, Laboratory evaluation of polycystic ovarian syndrome: the impact of insulin resistance and fat distribution on steroid and carbohydrate metabolism.
  • Deepa Narayanan, Hull Evaluation and implementation of biochemical markers of bone turnover in Idiopathic hypercalciuric renal stone formers
  • Lewis Couchman, London PTHrP measurement by Mass Spectrometric Immunoassay (MSIA)
  • Caroline Griffith, Leeds Iodine intake, metabolism and disposal in the first and third trimesters of pregnancy: a proof of principle study from North West England
  • Mathew Whitlock, Derby LC-MS/MS method for the determination of nitisinone (NTBC) in plasma and dried blood spots for the improved treatment monitoring of tyrosinaemia type I patients
  • Wycliffe Mbagaya, Leeds Biological variability of high sensitivity troponin in stable haemodialysis patients
  • John Shone, Dundee Investigation into the prevalence of Trichomonas vaginalis within the Scottish population: a comparison of traditional and molecular diagnostic techniques.

2011

  • Andrew Buckton, London. Pharmacogenomic dosage testing for anticoagulant therapy with clopidogrel and warfarin: an audit of clinical utility
  • Adrian Heaps, Cardiff. Investigating the impact of Filaggrin (FLG) gene mutations on the specific IgE antibody repertoire of individuals with moderate-severe atopic eczema (AE) using a protein allergen microarray.
  • Ed Hinchliffe, Manchester. Development of a method for the quantitation of tobramycin from dried blood spots by ultra high performance liquid chromatography tandem mass spectrometry
  • Satyanarayana Maddi, Salford. A systematic re-appraisal of the diagnostic utility of procalcitonin and IL-6: IL-10 ratio as rapid biomarkers of sepsis in critical illness.
  • Sarah Neale, Cardiff. Can MALDI TOF/TOF mass spectrometric analysis of serum thyroglobulin be used as a clinical assay?
  • Ceri Roberts, Oxford. Prognostic value of primary biliary cirrhosis-specific anti-nuclear antibodies in assessing response to ursodeoxycholic acid treatment.
  • Nick Unsworth, London. Development of a 4-hydroxy-2-oxoglutarate aldolase enzyme assay for the diagnosis of Primary Hyperoxaluria Type 3.

2010

  • Adrian Heaps, Cardiff. Analysis of the serum IgE repertoire in Hyper IgE Syndrome (HIES) patients using an Immuno Solid Phase Allergen Chip (ISAC)
  • Rachel Marrington, Cardiff. Development and implementation of a Capillary Electrophoresis-Tandem Mass Spectrometry (CE-MS/MS) method for measurement of HDL-C with comparison to ultracentrifugation
  • Sunita Sardiwal, Canterbury. What is the biological variation of bone-specific alkaline phosphatase in stable haemodialysis patients?
  • Angela Mallard, Truro. Comparison of detection rates and service cost for Down’s syndrome first-trimester combined screening using bloods taken at booking versus bloods taken at nuchal translucency measurement.
  • Amanda Perry, Exeter. Investigating urine C-peptide immunoassays: matrix effects, stability and standardisation.
  • Anthony Catchpole, Oxford. Can trauma-associated changes in circulating vitamin D-binding protein (Gc-globulin) affect circulating 25(OH)-vitamin D concentrations?

2009

  • James Logie, Wishaw. Analytical assessment of a kisspeptin assay and its clinical utility as a screening tool for pre-eclampsia
  • Natasha Djedovic, Harrow. Development of robust assays for the measurement of plasma renin activity and aldosterone using UPLC mass spectrometry
  • David Halsall, Cambridge. Validation of a synthetic macroprolactin complex as control material

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Updated 11 July 2016

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